<;P>;PROBLEM TO BE SOLVED: To identify a causative gene of a cyprinodont pc-mutant. <;P>;SOLUTION: A gene causing polycystic disease kidney in a cyprinodont is identified from a chromosome region by using a positional cloning method as the cyprinodont pc-mutant. The pc-gene is a transcription factor having five C2H2-type zinc finger regions, and is considered as a homologous gene of a human Gli-similar3 (Glis3) gene from the high homology at the zinc finger region. <;P>;COPYRIGHT: (C)2007,JPO&INPIT