agents and methods for recruitment of bone marrow-derived pluripotent stem cell into peripheral circulation

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专利权人:

GENOMIX CO., LTD.;OSAKA UNIVERSITY

发明人:

KATSUTO TAMAI,TAKEHIKO YAMAZAKI,TAKENAO CHINO,YASUFUMI KANEDA

申请号：

BRPI0911439

公开号：

BRPI0911439A2

申请日:

2009.04.30

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention for the first time demonstrated that: (1) bone marrow-derived pluripotent tissue stem cells can be induced in peripheral blood by intravenously administering tissue extract prepared from isolated skin pieces； (2) the substance in the isolated skin pieces, which is responsible for mobilizing bone marrow-derived pluripotent tissue stem cells to peripheral blood, is HMGB1； and (3) HMGB1 with the activity of mobilizing bone marrow-derived pluripotent stem cells to peripheral blood can be easily purified from cultured cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/