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Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation
专利权人:
Genomix Co., Ltd.;Osaka University
发明人:
Kaneda, Yasufumi,Tamai, Katsuto,Chino, Takenao,Yamazaki, Takehiko
申请号:
AU2009240884
公开号:
AU2009240884A8
申请日:
2009.04.30
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The following facts 1) to 3) are found; 1) when a tissue extract which is extracted from an isolated skin graft is administered intravenously, a bone-marrow-derived pluripotent stem cell can be induced in a peripheral blood; 2) the substance which can recruit the bone-marrow-derived pluripotent stem cell contained in the isolated skin graft into the peripheral blood is HMGB1; and 3) HMGB1 which has an activity to recruit the bone-marrow-derived pluripotent stem cell into the peripheral blood can be purified readily from cells in culture.
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