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COMPOSES MACROCYCLIQUES DE QUINOXALINYLE INHIBANT LES SERINE PROTEASES DE L'HEPATITE C
专利权人:
ENANTA PHARMACEUTICALS; INC.
发明人:
NAKAJIMA, SUANNE,SUN, YING,TANG, DATONG,XU, GOUYOU,PORTER, BRIAN,OR, YAT SUN,WANG, ZHE,MIAO, ZHENWEI
申请号:
CA2522561
公开号:
CA2522561C
申请日:
2004.04.16
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to compounds of Formula (I) or (II), or apharmaceutically acceptable salt, ester, or prodrug, thereof: formula (I),formula (II): which inhibit serine protease activity, particularly theactivity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, thecompounds of the present invention interfere with the life cycle of thehepatitis C virus and are also useful as antiviral agents. The presentinvention further relates to pharmaceutical compositions comprising theaforementioned compounds for administration to a subject suffering from HCVinfection. The invention also relates to methods of treating an HCV infectionin a subject by administering a pharmaceutical composition comprising thecompounds of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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