BOTELLA, GABRIEL MARTINEZ,HARRISON, BOYD L.,ROBICHAUD, ALBERT JEAN,SALITURO, FRANCESCO G.,BERESIS, RICHARD THOMAS
申请号:
SG11201609813X
公开号:
SG11201609813XA
申请日:
2015.05.29
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
and pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined herein, and A is a heteroaryl ring system comprising 3 or 4 nitrogens as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.