Papanikos, Alexandra,Willems, Marc,Storck, Pierre Henri,Ten Holte, Peter,Embrechts, Werner Constant Johan,Mevellec, Laurence Anne,Freyne, Eddy Jean Edgard
申请号：
AU2007274284
公开号：
AU2007274284B2
申请日:
2007.07.12
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention concerns the compounds of formula (I) the -oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Y represents -Calkyl-, -Calkyl-NR-Calkyl- or -Calkyl-NR-CO-Calkyl-； X represents -O-； X represents NR-Calkyl-； R represents hydrogen, halo or Het-O-； R represents hydrogen； R represents hydroxy, Calkyloxy- or Calkyloxy subst ituted with one or two substituents each independently selected from Het, hydroxy, Calkyloxy-, Calkyloxy-Calkyloxy and NRR； R represents hydrogen or Calkyl； R represents hydrogen or Calkyl； R represents hydrogen； R and R each independently represent hydrogen； Calkyl-S(=O)-Calkyl-C(=O)-； Calkyl or Calkyl substituted with hydroxy； Het represents pyridinyl optionally substituted with Calkyl； Het represents morpholinyl, piperidinyl or piperazinyl wherein said Het is optionally substituted with hydroxy-Calkyl or Calkyl-S(=O)-Calkyl-.
