Joseph E. Pero,Hannah D. G. F. Lehman,Mark E. Layton,Michael A. Rossi,Michael J. Kelly, III
申请号:
US14437142
公开号:
US09388179B2
申请日:
2013.10.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are compounds of Formula AA and Formula AB: wherein “Heteroaryl-1”, RA1, RA2, RB1, and RC are defined herein, which novel compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formulae AA and AB or their salts, and methods of treating neuropathic pain disorders using the same.