PERO, JOSEPH E.,LEHMAN, HANNAH D. G. F.,LAYTON, MARK E.,ROSSI, MICHAEL A.,KELLY, MICHAEL J., III
申请号:
CA2891056
公开号:
CA2891056A1
申请日:
2013.10.23
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Disclosed are compounds of Formula AA and Formula AB: wherein "Heteroaryl-1", RA1, RA2, RB1, and RC are defined herein, which novel compounds have properties for blocking Nav 1.7 ion channels found in peripherial and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formulae AA and AB or their salts, and methods of treating neuropathic pain disorders using the same.