N-SUBSTITUTED INDAZOLE SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS

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专利权人:

发明人:

申请号：

EP13849733.4

公开号：

EP2911663A1

申请日:

2013.10.23

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Disclosed are compounds of Formula AA and Formula AB: wherein &ldquoHeteroaryl-1&rdquo, RA1, RA2, RB1, and RC are defined herein, which novel compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formulae AA and AB or their salts, and methods of treating neuropathic pain disorders using the same.

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