Spector, Tom,Peters, William Paul,Kufe, Donald William,Huber, Brian
申请号:
AU2012200856
公开号:
AU2012200856B2
申请日:
2012.02.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2012200856B220131010.pdf#####DOCunw4-rnJ2a20i ABSTRACT Methods for improved administration and dosing of DPD inhibitors in combination with 5-FU and/or 5-FU prodrugs are provided, comprising first administering to a patient in need thereof a DPD inhibitor that substantially eliminates activity of the enzyme and thereafter administering 5-FU or a 5-FU prodrug, wherein the level of 5-FU or 5-FU prodrug is in substantial excess of DPD inhibitor in the patient.