Humanized anti-il-10 antibodies for the treatment of systemic lupus erythematosus (sle)

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专利权人:

BIOTEST AG

发明人:

CZELOTH NIKLAS,BRUECHER CHRISTOPH,ENGLING ANDRE,DAELKEN BENJAMIN,ROTTGEN PETER,ZUBER CHANTAL,GUTSCHER MARCUS,WESSELS-KRANZ JUDITH,WARTENBERG-DEMAND ANDREA,OSTERROTH FRANK,UHEREK CHRISTOPH

申请号：

NZ60089410

公开号：

NZ600894A

申请日:

2010.11.30

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed is a humanized antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof comprises a variable light chain comprising the amino acid sequences SEQ ID NO: 71, 72 and 73 (SSQNIVHSNGNTY, KVSNRFSGVPDR and GSHVPW respectively), and a variable heavy chain comprising the amino acid sequences SEQ ID NO: 74, 75 and 76 (ASGFSFATYG, IWRGGSTDYSAAFMSR and QAYGHYMD respectively).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/