SCHOENAFINGER, KARL,KEIL, STEFANIE,URMANN, MATTHIAS,MATTER, HANS,GLIEN, MAIKE,WENDLER, WOLFGANG
申请号:
AT08864630
公开号:
AT549332T
申请日:
2008.12.12
申请国别(地区):
AT
年份:
2012
代理人:
摘要:
The invention relates to cyclic N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARgamma agonist activity. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.