Ninkovic, Sacha,Crosignani, Stefano,Scales, Stephanie Anne,Mcalpine, Indrawan James,Collins, Michael Raymond,Maderna, Andreas,Wythes, Martin
申请号:
AU2016231832
公开号:
AU2016231832B2
申请日:
2016.03.17
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
A compound of Formula I is provided: or pharmaceutically acceptable enantiomers, salts or solvates thereof. The 5 invention further relates to the use of the compounds of Formula I as TDO2 inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer, neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease, chronic viral infections such as HCV and HIV, depression, and obesity. The invention also 10 relates to a process for manufacturing compounds of Formula I.