Sacha Ninkovic,Michael Raymond Collins,Stefano Crosignani,Andreas Maderna,Indrawan James McAlpine,Stephanie Anne Scales,Martin Wythes
申请号：
US15749963
公开号：
US20180222862A1
申请日:
2016.08.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A compound of Formula I is provided:or pharmaceutically acceptable enantiomers, salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as TDO2 inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer, neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease, chronic viral infections such as HCV and HIV, depression, and obesity. The invention also relates to a process for manufacturing compounds of Formula I.
