A shield remover for removing a needle shield (150/155) from a syringe (100), comprising: (a) an outer cap (350) having a tubular skirt member (352) arranged coaxially with the needle shield of the syringe (100), (b) an intermediary component (250) coupled between the outer cap (350) and the needle shield (150/155), the intermediary component (250) comprising a shield engagement grip means (254) for coupling the intermediary component (250) with the needle shield (150/155), and (c) a lock member (280). The outer cap (350) and the intermediary component (250) comprise a series of axially disposed detents (257) formed on one of the outer cap (350) and the intermediary component (250), and a retaining protrusion (357) formed on the other of the outer cap (350) and the intermediary component (250), wherein the retaining protrusion (357) is selectively engageable with each one of the series of axially disposed detents (257). The lock member (280) is configured for being received by the outer cap (350) and movable to a position wherein it maintains locking engagement between the retaining protrusion (357) and the selectively engaged one of the series of axially disposed detents (257).L'invention concerne un dispositif de retrait de protection pour retirer une protection d'aiguille (150/155) d'une seringue (100), qui comprend : (a) un capuchon externe (350) ayant un élément de jupe tubulaire (352) agencé de manière coaxiale avec la protection d'aiguille de la seringue (100), (b) un composant intermédiaire (250) couplé entre le capuchon externe (350) et la protection d'aiguille (150/155), le composant intermédiaire (250) comprenant un moyen de préhension de mise en prise de protection (254) pour coupler le composant intermédiaire (250) à la protection d'aiguille (150/155), et (c) un élément de verrouillage (280). Le capuchon externe (350) et le composant intermédiaire (250) comprennent une série de crans disposés axialement (257) formés sur le capuchon externe (350) ou le c