A compound having the formula ** Formula ** or a pharmaceutically acceptable salt thereof, wherein a dotted line represents the presence or absence of a bond: Y is CO2R2, CON (R2) 2, CON (OR2) 2 , CON (OR2) R2, CON (CH2CH2OH) 2, CONH (CH2CH2OH), CH2OH, P (O) (OH) 2, CONHSO2R2, SO2N (R2) 2, SO2NHR2, ** Formula ** where R2 is independently H , C1-C6 alkyl, unsubstituted phenyl, or unsubstituted biphenyl； A is - (CH2) 6-, cis-CH2CH>； = CH- (CH2) 3- or -CH2C≡C- (CH2) 3-, where 1 or 2 carbon atoms can be replaced with S or O； or A is - (CH2) m-Ar- (CH2) or-, where Ar is interarylene or heterointerarylene, the sum of myo is 1, 2, 3, or 4, and where a CH2 can be replaced with S or O ； wherein Interarylene or heterointerarylene refers to a ring-ring or ring system or a heteroaryl ring or ring system that connects two parts of a molecule, where the interarylene or heterointerarylene can be substituted or unsubstituted, where the unsubstituted or non-substituted interarylene It has substituents other than the two parts of the connecting molecule, where the interarylene or heterointerarilesin substitute has substituents in addition to the two parts of the connecting molecule, or where Ar is interphenylene, intertienylene, interfurylene, interpyridinylene, interoxasolylene and intertiazoliles to replace or replace .Un compuesto que tiene la fórmula**Fórmula** o una de sus sales farmacéuticamente aceptables, en donde una línea de puntos representa la presencia o la ausencia de un enlace: Y es CO2R2, CON(R2)2, CON(OR2)2, CON(OR2)R2, CON(CH2CH2OH)2, CONH(CH2CH2OH), CH2OH, P(O)(OH)2,CONHSO2R2, SO2N(R2)2, SO2NHR2, **Fórmula** en donde R2 es independientemente H, alquilo C1-C6, fenilo sin sustituir, o bifenilo sin sustituir； A es -(CH2)6-, cis-CH2CH>；=CH-(CH2)3- o -CH2C&equiv；C-(CH2)3-, en donde 1 ó 2 átomos de carbono pueden estarreemplazados con S u O； o A es -(CH2)m-Ar-(CH2)o-, en donde Ar es interarileno o heterointerarileno, la suma de m y o es 1, 2, 3, ó 4, y endonde un CH2
