The invention relates to a biological preparation comprising orthosilicic and silicic acid, a primary (“constant/first”) osmolyte choline and a weak alkalinizing agent without free hydroxyl groups and to a method for preparing the preparation, comprising: i) hydrolyzing a silicon comprising choline solution thereby forming a choline stabilized orthosilicic acid and oligomers solution； ii) alkalizing the choline orthosilicic acid and oligomers solution by adding a weak alkalizing agent without hydroxyl groups； and iii) optionally adding a divalent trace element and/or secondary osmolyte, to biological preparation obtainable and its uses.
