This invention comprises a method of using for anti-pathogenesis effect an improved composition and an improved composition comprising heat stable plant juice soluble plant proteins； the improvement comprising that the composition comprising heat stable plant juice soluble plant protein is essentially a water insoluble concentrated mass free from components more soluble in the plant juice, and enriched in heat stable proteins of the plant juice； dosage forms made from the composition for using for Adiponectin agonist effect for reducing the risk of one or more of a disorder selected from Type II diabetes, hyperlipidemia, atherosclerosis, hypertension, heart disease and obesity and for anti-microbial effect for reducing the risk of or treating the microbial infections in plants and animals, with or without synergistic interaction with other antimicrobial agents. This invention comprises a composition essentially characterized by Infra-red absorption spectrum provided therein.
