PARISOT ALEXIS GUY ANDRE,DESGOUILLES-BLECHET STEPHANIE MARIE-CATHERINE,CHARREYRE CATHERINE,ROULET CLAUDE JEAN MARIE
申请号：
IN7813/DELNP/2007
公开号：
IN278719B
申请日:
2007.10.10
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to oil-in-water emulsions, their use as adjuvants, and pharmaceutical, immunologic, or vaccine compositions that may comprise the same. In one embodiment, the oil-in-water (O/W) emulsion may comprise an aqueous solution containing an immunogen, a mineral oil, a non-ionic lipophilic ethoxylated fatty alcohol and a non-ionic hydrophilic surfactant. In another embodiment, the oil-in-water (O/W) emulsion may comprise an aqueous solution containing an immunogen, a non-ionic lipophilic surfactant, a mineral oil and a non-ionic hydrophilic ethoxylated fatty alcohol. The present invention also encompasses a method of making a vaccine composition using the adjuvant of the instant invention, the vaccine composition so obtained and methods of use.
