Parisot, Alexis Guy Andre,Desgouilles-Blechet, Stephanie Marie-Catherine,Charreyre, Catherine,Roulet, Claude Jean Marie
申请号：
AU2010206041
公开号：
AU2010206041B2
申请日:
2010.07.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2010206041B220120802.pdf#####ABSTRACT The present invention relates to oil-in-water emulsions, their use as adjuvants, and pharmaceutical, immunologic, or vaccine compositions that may comprise the same. In one embodiment, the oil-in-water (OAV) emulsion may comprise an aqueous 5 solution containing an immunogen, a mineral oil, a non-ionic lipophilic ethoxylated fatty alcohol and a non-ionic hydrophilic surfactant. In another embodiment, the oil-inwater (OAV) emulsion may comprise an aqueous solution containing an immunogen, a non-ionic lipophilic surfactant, a mineral oil and a non-ionic hydrophilic ethoxylated fatty alcohol. The present invention also encompasses a method of making a vaccine 10 composition using the adjuvant of the instant invention, the vaccine composition so obtained and methods of use.
