Benzoxazepin PI3K inhibitor compounds and methods of use

• 收藏
• 分享

专利权人:

F. Hoffmann-La Roche AG

发明人:

申请号：

EP14190276.7

公开号：

EP2845592A1

申请日:

2010.09.27

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention relates to benzoxazepin compounds of Formula Iincluding stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z1 is CR1 or N； Z2 is CR2 or N； Z3 is CR3 or N； Z4 is CR4 or N； and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/