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Benzoxazepine compounds PI3K inhibitors and their use in cancer treatment
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
BLAQUIERE, NICOLE,DO, STEVEN,DUDLEY, DANETTE,FOLKES, ADRIAN J.,HEALD, ROBERT,HEFFRON, TIMOTHY,JONES, MARK,KOLESNIKOV, ALEKSANDR,NDUBAKU, CHUDI,OLIVERO, ALAN G.,PRICE, STEPHEN,STABEN, STEVEN,WANG, LAN
申请号:
ES10757213
公开号:
ES2444779T3
申请日:
2010.09.27
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Compounds of the formula I: stereoisomers, gometric isomers, tautomers and pharmaceutically acceptable salts thereof, in which: Z1 is CR1 or N; Z2 is CR2 or N; Z3 is CR3 or N; Z4 is CR4 or N; B is a pyrazolyl, imidazolyl or triazolyl ring fused with the benzoxazepine ring and chosen from the structures: ** Formula **Compuestos de la fórmula I: estereoisómeros, isómeros g 5 eométricos, tautómeros y sales farmacéuticamente aceptables de los mismos, en laque: Z1 es CR1 o N; Z2 es CR2 o N; Z3 es CR3 o N; Z4 es CR4 o N; B es un anillo pirazolilo, imidazolilo o triazolilo fusionado con el anillo de la benzoxazepina y elegido entre lasestructuras:**Fórmula**
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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