XINXHAO CHEN,SCOTT ALAN FRANK,DAVID MICHAEL REMICK,STEVEN WAYNE PEDERSEN
申请号：
CR20110669
公开号：
CR20110669A
申请日:
2011.12.12
申请国别(地区):
CR
年份:
2012
代理人:
摘要：
Described are compounds of formula Graduates, trans-4 - [[(5S) - 5 - [[[3,5-bis (trifluoromethyl) phenyl] methyl] (2 - methyl - 2h-tetrazol-5-yl) amino] - 2,3,4,5 - tetrahydro - 7.9 - dimethyl - 1H - 1 - 1 - benzazepin - il] methyl] - ciclohexancarbox u00edlico, as a free Acid or a pharmaceutically acceptable Salt thereof, HI Drato and hydrate in Crystalline form, Pharmaceutical formulations and Methods of use.Se describen compuestos de fórmula titulados, ácido trans-4-[[(5S)-5-[[[3,5-bis(trifluorometil)fenil]metil] (2-metil-2H-tetrazol-5-il)amino]-2,3,4,5-tetrahidro-7,9-dimetil-1H-1-benzazepin-1-il]metil]-ciclohexancarboxílico, como un ácido libre o una sal del mismo farmacéuticamente aceptable, hidrato, e hidrato en forma cristalina； formulaciones farmacéuticas； y métodos de uso.
