DAVID MICHAEL REMICK,STEVEN WAYNE PEDERSEN,SCOTT ALAN FRANK,XINCHAO CHEN
申请号：
MX2011014024
公开号：
MX2011014024A
申请日:
2010.06.28
申请国别(地区):
MX
年份:
2012
代理人:
摘要：
Abstract Compounds of a formula entitled, trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2H-tetrazol- 5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-y l]methyl]- cyclohexanecarboxylic acid, as a free acid or a pharmaceutically acceptable salt thereof, hydrate, and hydrate in crystalline form； pharmaceutical formulations； and methods of use are disclosed.Se describen ácido trans-4-[[(5S)-5-[[[3,5-bis(trifluorometil) feniI]metil](2-metil-2 H-tetrazol-5-iI)amino]-2 ,3,4, 5-tetrahidro-7 ,9- dimetil-1 H-1 -benzazepin-1-iI]metil]-ciclohexa ncarboxilico, así como un ácido libre o una sal farmacéuticamente aceptable del mismo, hidrato, e hidrato en forma cristalina； formulaciones farmacéuticas, y métodos de uso.
