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L'ACIDE TRANS-4-[[(5S)-5-[[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHYL] (2-METHYL-2H-TETRAZOL-5-YL)AMINO]-2,3,4,5-TETRAHYDRO-7,9-DYMETHYL-1H-1-BENZAZEPIN-1-YL]METHYL]-CYCLOHEXANECARBOXYLIQUE
专利权人:
ELI LILLY AND COMPANY
发明人:
申请号：
EP10728558.7
公开号：
EP2448933B1
申请日:
2010.06.28
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Compounds of a formula entitled, trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid, as a free acid or a pharmaceutically acceptable salt thereof； and hydrates and other solvates in crystalline form； pharmaceutical formulations； and methods of use are disclosed.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
相关专利
Trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid
TRANS-4[(5S)-5[[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHYL](2-METHYL-2H-TETRAZOL-5-YL)AMINO]-2,3,4,5-TETRAHYDRO-7,9-DIMETHYL-1H-1-BENZAZEPIN-1-YL]METHYL]-CYCLOHEXANECARBOXYLIC ACID
Trans-4 - [[(5 S) -5 - [[[3,5-bis (trifluoromethyl) phenyl] methyl] (2-methyl-2H-tetrazol-5-yl) amino] -2,3,4,5 -tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl] methyl] cyclohexanecarboxylic acid
(2-methyl-2h-tetrazol-5-yl) amino] -2,3,4-trans [4 (5s) -5 - [[[3,5-bis (trifluoromethyl) phenyl] methyl] trans] 5-Tetrahydro-7,9-dimethyl-1h-1-benzazepin-1-yl] methyl] cyclohexanecarboxylic acid
TRANS-4-[[(5S)-5-[[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHYL](2-METHYL-2H-TETRAZOL-5-YL)AMINO]-2,3,4,5-TETRAHYDRO-7,9-DIMETHYL-1H-1-BENZAZEPIN-1-YL]METHYL]-CYCLOHEXANECARBOXYLIC ACID
