QUAN YING SHU,OOYA TOORU,JIANG RONGRONG,KAMIYAMA FUMIO
申请号：
IN201837004710
公开号：
IN201837004710A
申请日:
2018.02.07
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
A DDS carrier that allows the sustained release of a drug and a method for producing the same. The present invention is characterized in that a drug is held in a PEG carboxy group containing polymer graft. A carboxy group containing polysaccharide can be used suitably among the polymers. The PEG carboxy group containing polymer graft is a compound in which polyethylene glycol is grafted to a carboxy group containing polymer. When a carboxy group containing polysaccharide is used a polymer graft can be produced by utilizing a condensation reaction between aminated PEG and a carboxy group containing polysaccharide in the presence of a triazine condensing agent. A PEG carboxy group containing polysaccharide graft can also be produced by utilizing a condensation reaction between PEG and a carboxy group containing polysaccharide in the presence of an acid.
