SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES;SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.
发明人:
YANG, CHUNHAO,MENG, LINGHUA,CHEN, YANHONG,WANG, XIANG,TAN, CUN,LI, JIAPENG,DING, JIAN,CHEN, YI
申请号：
CA2874062
公开号：
CA2874062A1
申请日:
2013.04.23
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
