1. A process for preparing a pharmaceutical composition comprising a biologically active protein comprising the steps of: providing an aqueous composition comprising a solvent, the biologically active protein and between 20% by weight and 60% by weight of non-polymeric sugar, freezing the composition to form at least one of the frozen substance comprising a solvent in frozen form, premises frozen substances in a drying apparatus with a finding on the substrate, wherein the substrate comprises one or more retention mechanisms that determined yayut one or more borders of the substrate, wherein a maximum of 30% of the surface material is contacted with one or more retaining mechanism, reducing the pressure in the drying apparatus is below atmospheric pressure, providing heating of the material for the purpose of sublimation of the frozen solvent and obtain a dried substance veschestva.2. The method of claim. 1, characterized in that the frozen solvent sublimes less than 48 p.3. A method according to claim. 2, characterized in that the frozen solvent sublimes less than 36 p.4. A method according to claim. 3, characterized in that the frozen solvent sublimes less than 16-24 p.5. A method according to Claim. 1, wherein a maximum of 20% of the surface material is contacted with one or more retaining podlozhki.6 mechanism. The method of claim. 5, characterized in that maximally 10% of the surface material is contacted with one or more retaining podlozhki.7 mechanism. A method according to Claim. 1, wherein the frozen material is a sferoid.8. A method according to Claim. 1, wherein the substrate holding mechanism is the bottom, the material lies on the bottom, and the substrate is open to allow free passage of radiation to said bottom,1. Способ получения лекарственного средства, включающего биологически активный белок, включающий стадии:предоставления водной композиции, включающей растворитель, биологически активный белок и между 20% по массе и 60% по массе неполимерного сах
