Described are deuterium-substituted oxazepin compounds of structural Formula I, which are inhibitors/blockers of the late sodium current. Also described are pharmaceutical compositions comprising the deuterium-substituted oxazepin compounds, and methods of use thereof.本發明揭示結構式I之經氘取代之氧氮呯化合物,其為晚鈉電流抑制劑/阻斷劑。亦描述包含該等經氘取代之氧氮呯化合物之醫藥組合物及其使用方法。無