Cytune Pharma;Inserm (Institut National de la Sante et de la Recherche Medicale)
发明人:
Morisseau, Sebastien Daniel,Teppaz, Geraldine,Jacques, Yannick Laurent Joseph,Robert, Bruno Gilbert Marc,De Martynoff, Guy Luc Michel,Bechard, David
申请号:
AU2012272138
公开号:
AU2012272138B2
申请日:
2012.06.22
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof.