CYTUNE PHARMA;UNIVERSITE PARIS DESCARTES;ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
发明人:
Alain GEY,Eric TARTOUR,David BECHARD
申请号:
US14910475
公开号:
US20160175459A1
申请日:
2014.08.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an immunomodulatory antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof; and uses thereof.