DIAZ FERNANDEZ, José Luis,CUBERES ALTISENT, Mª Rosa
申请号：
ES13709789
公开号：
ES2687518T3
申请日:
2013.02.21
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A compound of general formula (I): ** Formula ** in which 5 R1 and R2 independently represent hydrogen； a saturated or unsaturated, branched or unbranched aliphatic C1-10 radical； an unsubstituted aryl； an unsubstituted heteroaryl radical； a C3-9 cycloalkyl radical optionally containing at least one heteroatom as a ring member selected from N, O or S and optionally substituted with a C1-6 alkyl group, a phenyl group, a benzyl group, a linear C1-6 alkoxy group or branched, -F, -Cl, -I, -Br, -CF3, -CH2F, -CHF2, -CN, -OH, -SH, -NH2, oxo, - (C>； = O) R ', -SR ', -SOR', -SO2R ', -NHR', -NR'R 'so that R' and optionally R '' for each substituent independently represents a linear or branched C1-6 alkyl group； a C1-10 cycloalkylalkyl radical； a C1-10 arylalkyl radical； or a C1-10 heteroarylalkyl radical； or R1 and R2 together with the bridging nitrogen form a C3-9 cycloalkyl optionally containing at least one additional heteroatom as a ring member selected from N, O or S and optionally substituted with a C1-6 alkyl group, a C1- alkoxy group 6 linear or branched, -F, -Cl, -I, -Br, -CF3, -CH2F, -CHF2, -CN, -OH, -SH, - NH2, oxo, - (C>； = O) R ', -SR ', -SOR', -SO2R ', -NHR', -NR'R 'so R' and optionally R '' for each substituent independently represents a linear or branched C1-6 alkyl group or with a group selected from: ** Formula ** or R1 and R2 together with the bridge nitrogen form C3-9 cycloalkyl optionally containing at least one additional heteroatom as a ring member selected from N, O or S, which can be condensed to form a system of rings with another C3-9 cycloalkyl optionally containing at least one heteroatom as a ring member selected from N, O or S； or that can be condensed to form a ring system with an aryl radical； or which can be spirocondensed with an aryl or heteroaryl group； R3 represents hydrogen or halogen； n is 0, 1 or 2； m is 1, 2, 3 or 4； and ----- represents an optionally double bond； with the proviso that when R1 and R2 together with the bridge nitro
