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4,5-dihydro-oxazol-2-yl derivatives
专利权人:
F. Hoffmann-La Roche AG
发明人:
Annick Goergler,Guido Galley,Katrin Groebke Zbinden,Roger Norcross
申请号:
BRPI0916363
公开号:
BRPI0916363A2
申请日:
2009.07.15
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention relates to compounds of formula I wherein R1, R2, X, Y, and n are defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The invention also provides pharmaceutical compositions and methods of manufacture of such compounds. The compounds are useful for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases are depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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