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4,5-Dihydro-oxazol-2-yl derivatives
专利权人:
エフ.ホフマン-ラ;アーゲー;ロシュ;エフ.ホフマン-ラ ロシュ アーゲー
发明人:
ガレイ,グイド,ゴーグレー,アニック,グレープケ・ツビンデン,カトリン,ノークロス,ロジャー,ガレイ,グイド,ゴーグレー,アニック,グレープケ・ツビンデン,カトリン,ノークロス,ロジャー
申请号:
JP2011519122
公开号:
JP5547187B2
申请日:
2009.07.15
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
The invention relates to compounds of formula I wherein R1, R2, X, Y, and n are defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The invention also provides pharmaceutical compositions and methods of manufacture of such compounds. The compounds are useful for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases are depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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