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4,5-dihydro-oxazol-2yl derivatives
专利权人:
Guido Galley
发明人:
Guido Galley,Annick Goergler,Katrin Groebke Zbinden,Roger Norcross
申请号:
US13033645
公开号:
US08729113B2
申请日:
2011.02.24
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to compounds of formula IwhereinR1, R2, X, Y, and n are defined in the specification and to pharmaceutically acceptable acid addition salts thereof. The invention also provides pharmaceutical compositions and methods of manufacture of such compounds. The compounds are useful for the treatment of diseases related to the biological function of the trace amine associated receptors, which diseases are depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinsons disease, neurodegenerative disorders, Alzheimers disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
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中国工程科技知识中心
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