PEREIRA RAMOS, BENIGNO,PEREIRA RODRIGUEZ, ANGEL,ESTEVEZ TELLE, NATALIA,FUCIÑOS GONZALEZ, JUAN PABLO,RUA RODRIGUEZ, MARIA LUISA,PASTRANA CASTRO, LORENZO
申请号:
PL11842461
公开号:
PL2728011T3
申请日:
2011.07.27
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
The present invention relates to an optimized method for obtaining ACE activity inhibitory peptides wherein it includes the steps of whey ultrafiltration for obtaining a whey concentrate, enzymatic hydrolysis, hydrolysate ultrafiltration and inhibitory peptide separation, which comprises selecting and adding a mixture having suitable proportion and amount of two microbial proteases and having complementary action to said whey concentrate for the hydrolysis thereof in order to obtain peptides with an ACE inhibition percentage greater than 70% and an IC 50 index of 30 to 100 µg/ml.