KIM YONG IL,NA YOUNG JUN,KIM MIN JUNG,KIM YOUNG HUN,PARK JAE HYUN,WOO JONG SOO
申请号：
IN10775/DELNP/2012
公开号：
IN2012DN10775A
申请日:
2012.12.11
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
Provided is a pharmaceutical formulation in the form of bilayered tablets consisting of a first layer containing irbesartan or pharmaceutically acceptable salts thereof and a second layer containing an HMG CoA reductase inhibitor and a basic additive which can improve the dissolution rate and stability of irbesartan and an HMG CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.
