KIM,YONG II,NA, YOUNG JUN,KIM, MIN JUNG,KIM, YOUNG-HUN,PARK, JAE HYUN,WOO, JONG SOO
申请号：
MYPI 2012004511
公开号：
MY157307A
申请日:
2011.05.13
申请国别(地区):
MY
年份:
2016
代理人:
摘要：
PROVIDED IS A PHARMACEUTICAL FORMULATION IN THE FORM OF A BILAYERED TABLET CONSISTING OF A FIRST LAYER CONTAINING IRBESARTAN OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND A SECOND LAYER CONTAINING AN HMG-COA REDUCTASE INHIBITOR AND A BASIC ADDITIVE, WHICH CAN IMPROVE THE DISSOLUTION RATE AND STABILITY OF IRBESARTAN AND AN HMG-COA REDUCTASE INHIBITOR TO ENHANCE THE BIOAVAILABILITY OF THE DRUG COMPARED TO CONVENTIONAL COMPLEX FORMULATIONS AND TO MINIMIZE THE GENERATION OF THE RELATED COMPOUNDS, THEREBY BEING EFFECTIVELY USED AS A STABLE AND SUPERIOR THERAPEUTIC AGENT FOR HYPERTENSION AND HYPERCHOLESTEROLEMIA.
