KIM, YONG IL,NA, YOUNG JUN,KIM, MIN JUNG,KIM, YOUNG-HUN,PARK, JAE HYUN,WOO, JONG SOO
申请号：
SG2012087227
公开号：
SG185778A1
申请日:
2011.05.13
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
Provided is a pharmaceutical formulation in the form of bilayered tablets consisting of a first layer containing irbesartan or pharmaceutically acceptable salts thereof and a second layer containing an HMG-CoA reductase inhibitor and a basic additive, which can improve the dissolution rate and stability of irbesartan and an HMG-CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds, thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.
