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BICYCLIC HETEROCYCLIC AMIDE DERIVATIVE
专利权人:
LTD.;SUMITOMO DAINIPPON PHARMA CO.
发明人:
BAN, Hitoshi,KUSAGI, Manabu,TAKANASHI, Yosuke,HASEGAWA, Futoshi
申请号:
PH12017502408
公开号:
PH12017502408A1
申请日:
2017.12.22
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
The present invention provides: a bicyclic heterocyclic amide derivative that is represented by formula (1), that shows excellent cancer cell sphere forming ability suppressing effect, and that is useful as an orally administrable antitumor agent; and a pharmaceutically acceptable salt thereof. [In the formula: ring Q1 represents an optionally substituted C6-10 aryl group or the like; R1 and R2 independently represent a hydrogen atom or the like; W1 represents an optionally substituted C1-4 alkylene group; W2 represents -NR3aC(O)- or the like (wherein, R3a represents a hydrogen atom or a C1-6 alkyl group); Cy1 represents a group represented by formula (11) or the like; ring Q2 represents an optionally substituted benzene ring or the like; n and m each independently represent 0, 1, or 2; n and m are not simultaneously 0; X represents NR5 or the like; R5 represents a hydrogen atom or the like; p represents 1, 2, 3, 4, or 5; and R4 represents, independently when more than one thereof exists, a hydrogen atom or the like.]
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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