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POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5
专利权人:
Swedish Orphan Biovitrum AB (publ)
发明人:
BERGHARD, Charlotta,BERGLUND, Magnus,STRÖMBERG, Patrik,LINDBORG, Malin,GUNNERIUSSON, Elin,FELDWISCH, Joachim
申请号:
MYPI 2014702257
公开号:
MY167232A
申请日:
2013.02.19
申请国别(地区):
MY
年份:
2018
代理人:
摘要:
The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX₂X₃X₄A X₆X₇EID X₁₁LPNL X₁₆X₁₇X₁₈QW X₂₁AFIX₂₅ X₂₆LX₂₈D, and ii) an amino acid sequence which has at least 86 % identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatments.
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