BERGHARD, CHARLOTTA,BERGLUND, MAGNUS,STR�MBERG, PATRIK,LINDBORG, MALIN,GUNNERIUSSON, ELIN,FELDWISCH, JOACHIM
申请号：
PH12014501604
公开号：
PH12014501604A1
申请日:
2014.07.11
申请国别(地区):
PH
年份:
2014
代理人:
摘要：
The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86 pcnt identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatments.
