POLYPEPTIDES SE LIANT AU COMPLÉMENT HUMAIN C5

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专利权人:

Swedish Orphan Biovitrum AB (Publ)

发明人:

申请号：

EP18213025.2

公开号：

EP3511339A1

申请日:

2013.02.19

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected fromi) EX2X3X4A X6X7EID X11LPNL X16X17X18QW X21AFIX25 X26LX28D, andii) an amino acid sequence which has at least 86 % identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatments.

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