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NON-CYTOTOXIC MODIFIED CELLS AND USE THEREOF
专利权人:
THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
发明人:
Alon MONSONEGO,Angel PORGADOR,Roee ATLAS
申请号:
US16340196
公开号:
US20190233516A1
申请日:
2017.10.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.
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