THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
发明人:
MONSONEGO, ALON,PORGADOR, ANGEL,ATLAS, ROEE
申请号:
CA3039774
公开号:
CA3039774A1
申请日:
2017.10.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Modified cells comprising a transmembrane polypeptide comprising at least one extracellular target receptor-binding domain, a transmembrane domain and an intracellular domain, wherein said intracellular domain is not capable of transducing any signal are provided. Methods of inducing or inhibiting signaling by a target receptor in a target cell comprising contacting the target cell with a modified cell of the invention are also provided.