Samir N. Khleif,MIKAYEL MKRTICHYAN,IRYNA LEBEDYEVA
申请号：
US16737229
公开号：
US20200147091A1
申请日:
2020.01.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Several compounds have been discovered that modulate signal transduction through the PD-1 receptor. In certain embodiments, the compounds promote or induce an activating signal through the PD-1 receptor that activates a T cell. The compounds can bind to PD-1 and inhibit or prevent ligands from binding to PD-1 and thereby suppress inhibitory signal transduction through the PD-1 receptor.
