BILODEAU, Mark T.,SIMCOX, Mary,WHITE, Brian H.,KADIYALA, Sudhakar,WOOSTER, Richard
申请号：
EP17783109
公开号：
EP3442592A4
申请日:
2017.04.13
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Conjugates of an active agent attached to a neurotensin receptor-binding targeting moiety via a linker have been designed. Nanoparticles and microparticles comprising such conjugates can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or other diseases.
