PCT No. PCT/JP95/00490 Sec. 371 Date Oct. 20, 1995 Sec. 102(e) Date Oct. 20, 1995 PCT Filed Mar. 17, 1995 PCT Pub. No. WO95/25279 PCT Pub. Date Sep. 21, 1995A process for easily producing a packing material for high-performance liquid chromatography, which produces only a small amount of a dissolved matter. The process has a low cost and contributes to an improvement in the quality of the separated product, without reducing the separation capacity in the field of the separation of only a small amount of a dissolved matter derived from the polysaccharide derivative is obtained by washing the packing material comprising a polysaccharide coated on a carrier with a solvent.