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Heterocyclic compounds as a series of protein inhibitors
专利权人:
NOVARTIS AG
发明人:
PARKER, DAVID THOMAS,SEEPERSAUD, MOHINDRA,RADETICH, BRANKO,YIFRU, AREGAHEGN,RAMAN, PRAKASH,FU, JIPING,PATANE, MICHAEL,ZHENG, RUI,SIMIC, OLIVER,BRANDL, TRIXI,RIGOLLIER, PASCAL,LENOIR, FRANCOIS
申请号:
PE2012000534
公开号:
PE20121157A1
申请日:
2007.04.10
申请国别(地区):
PE
年份:
2012
代理人:
摘要:
It's an abiotic formula compound,N and y are 1; R14 is C (o);R1 IS H OR C1-C4 ALKYL; R2 IS C1-C4 ALKYL, C (O) C1-C4 ALKYL, C (O) OR C1-C4 ALKYL, AMONG OTHERS; W ES C (O) -C (O) H, C (O) -C (O) -AMINE, AMONG OTHERS; V IS Q1-Q2; Q1 IS C (O),N (H),N (C1-C4 tar),Q2 is h, C1-C4, or C1-C4, NH2, etc.; R3 is h, or C1-C4, and residue is a group (I),Page: 1(III)Among them, R8, R9 and R10 are h, C1-C4 tar, c3-c6-c0-c4 tar, R11 is h, R12 is cycloquilo C3-C6, R13 is h. These compounds can be used in the treatment of hepatitis C virus.REFERIDA A UN COMPUESTO HETEROCICLICO DE FORMULA (I), DONDE n E y SON 1; R14 ES C(O); R1 ES H O ALQUILO C1-C4; R2 ES ALQUILO C1-C4, C(O)ALQUILO C1-C4, C(O)OALQUILO C1-C4, ENTRE OTROS; W ES C(O)-C(O)H, C(O)-C(O)-AMINA, ENTRE OTROS; V ES Q1-Q2; Q1 ES C(O), N(H), N(ALQUILO C1-C4), ENTRE OTROS; Q2 ES H, ALQUILO C1-C4, O-ALQUILO C1-C4, NH2, ENTRE OTROS; R3 ES H O ALQUILO C1-C4; EL RESIDUO DIVALENTE (a) ES UN GRUPO (i), (ii), (iii), ENTRE OTROS; R8, R9 Y R10 SON H, ALQUILO C1-C4, CICLOALQUIL C3-C6-ALQUILO C0-C4; R11 ES H; R12 ES CICLOALQUILO C3-C6; R13 ES H. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DEL VIRUS DE LA HEPATITIS C
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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