The present invention relates to tetraline and indane derivatives of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such tetraline and in-dane derivatives, and the use of such tetraline and indane derivatives for therapeutic pur-poses. The tetraline and indane derivatives are GlyT1 inhibitors.本發明係關於式(I)四氫萘及二氫茚衍生物或其生理學上容許之鹽。本發明係關於包含此種四氫萘及二氫茚衍生物之醫藥組合物,及此種四氫萘及二氫茚衍生物用於治療目的之用途。該等四氫萘及二氫茚衍生物為GlyT1抑制劑。